Apr 212015
Structure of the clathrin and clathrin-adaptors when a vesicle is formed. IMAGE: Skruzny, Desfosses, Prinz et al. Developmental Cell 2015

Structure of the clathrin and clathrin-adaptors when a vesicle is formed. IMAGE: Skruzny, Desfosses, Prinz et al. Developmental Cell 2015

Ground-breaking microscopy techniques have enabled scientists at EMBL Heidelberg to shed new light on how cells perform endocytosis – a function that is key to many cellular processes, such as ingesting nutrients and cell-signalling.

The process of endocytosis generates bubble-like membrane vesicles that surround the molecules to be ingested and move them from the cell surface into the cell. In this study, published in Developmental Cell, a cross-disciplinary team from five research groups at EMBL and the European XFEL demonstrates the significance of a particular type of proteins, called clathrin adaptor proteins, to the process.

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Apr 172015
copyright https://lilbubome.wordpress.com/

Have you ever thought about contributing to the sequencing of a complete animal genome? What information could you read out of such a genome sequence and how much would the sequencing cost?

EMBL Alumna Uschi Symmons wants to exactly do that and aims to raise money to sequence the genome of Internet celebrity cat ‘Lil Bub’. She and her colleagues would like to use the sequence information to study combinations of traits in the LilBubome such as polydactyly and osteopetrosis.

Read more about this interesting project on EMBLetc. or have a look at the LilBUBome website.

Feb 092015

ELLS LearningLAB “Structural biology – shining light onto the fabric of life”

Blue skies, sunshine, snow and protein crystals all around! ELLS has just started its LearningLAB “Structural biology – shining light onto the fabric of life” at EMBL Grenoble. The group of international secondary school science teachers is looking forward to exploring the world of biological structures, crystallography and synchrotron radiation during the next days.




Feb 062015
EMBL Insight Lecture 2014: now available as video-on-demand

Did you miss the EMBL Insight Lecture 2014 by Dr. Cornelius Gross on “Why do we do what we do? Exploring the neural basis of emotions”?  We are pleased to announce that the video of Cornelius’ talk is now available on EMBLog, where it can be viewed on demand. The media player provides the option to

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Feb 042015
Applications invited for ELLS LearningLAB in Athens, Greece

Apply now for the ELLS LearningLAB in Athens – 25-26 April 2015! The European Learning Laboratory for the Life Sciences (ELLS), in collaboration with the Institute of Biosciences & Applications at the National Center for Scientific Research “Demokritos” and the Directorate of Secondary Education of Piraeus, invites Greek-speaking secondary school science teachers to apply for the ELLS

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Jan 212015
Multi-directional evolution: the ELLS TeachingBASE is growing!

  If you are looking for a place of innovative, ready-made teaching resources for the biology classroom, look no further than the ELLS TeachingBASE. Our collection of teaching modules produced by EMBL scientists and ELLS education specialists feature both practical classroom activities as well as computational modules – and it is growing continuously! The latest

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Oct 202014
From worm muscle to spinal discs

 An evolutionary surprise Thoughts of the family tree may not be uppermost in the mind of a person suffering from a slipped disc, but those spinal discs provide a window into our evolutionary past. They are remnants of the first vertebrate skeleton, whose origins now appear to be older than had been assumed. Scientists at

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Oct 132014
Registration now open for EMBL Insight Lecture live streaming

Have you ever wondered why we do what we do?…biologically speaking, of course. On Friday 5th December 2014 Cornelius Gross, EMBL group leader, will attempt to answer this question from a neuroscientific point of view in this year’s EMBL Insight Lecture entitled “Why do we do what we do? Exploring the neural basis of emotions”.

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Oct 102014
log2EMBL: 26 biology teachers explored virtual research institute

26 German secondary school biology teachers gathered at EMBL Heidelberg last week to attend the LearningLAB “Log in to Science – Forschern auf der Spur: Forschungssimulation am Beispiel der Eisenspeicherkrankheit (Hämochromatose)” – a joint CPD course organised by ELLS, the out-of-school lab ExploHeidelberg, and the Regierungspräsidium Karlsruhe (regional administrative council).
Over two days, teachers had the opportunity to explore the virtual research institute log2EMBL which has been developed by teachers, students and ELLS staff as part of the Robert Bosch Stiftung-funded iNEXT (interactive Network for Experimental Training) project. iNEXT has been a 3-year project to develop and disseminate state-of-the-art resources for teaching molecular biology at the advanced level in German schools (www.inext-embl.de).
The virtual research institute log2EMBL is a platform to offer inquiry-based research projects for students.

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Sep 162014
Public film event in Heidelberg

Cell fate: Journeys to specialisation Have you ever wondered how cells differentiate into specific cell types? How do our blood, skin and muscle cells get their distinct abilities and shapes? And how are these processes controlled on a molecular and cellular level? Join us on Sunday 12th October 2014 at 18:00 at the Deutsch-Amerikanisches Institut

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Sep 082014
Scientists for a day

For just one day, PhD students could no longer claim the title of ‘youngest researchers’ at EMBL. That honour went to the 13 students aged 11 to 17 who conducted a full-day experiment in the EMBL training labs as part of the Tschira-Jugendakademie at the end of August this year. Initially created as a one-time

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Sep 032014
Will we ever win the race against all the viruses?

As a fresh outbreak of Ebola takes its toll in West Africa, I ask myself why we know a lot about viruses and yet do not have a vaccine or a drug against a lot of them. A little over two hundred years ago, in 1796, Edward Jenner developed the first antiviral vaccine to treat smallpox virus and since then scientists have developed vaccines for various viral diseases such as measles, mumps, rubella, polio, hepatitis, influenza and rotavirus. However, we still have no vaccines against the common cold and many other, often deadly, viral infections such as Lassa, Marburg, SARS and H1N1. This seems perplexing at first, but let’s take a closer look into why handling a virus is not just challenging but actually quite tricky.

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Aug 292014
Fascinated by proteins? Join the next ELLS Webinar!

Have you ever wondered what proteins look like on the molecular level? Are you curious what methods scientists use to find out? If you are keen to get an insight into the fascinating world of protein X-ray crystallography, the next ELLS webinar by EMBL visiting scientist Kanchan Anand will present the ideal opportunity! Don’t worry,

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Aug 052014
Ask EMBL… anything!

Have you ever wondered… How do you pronounce “Helicobacter pylori”? How does genetic sequencing work? How do I become the director general of a top international research facility? As part of our 40th anniversary celebration, we’re asking you to ask EMBL…anything! Submit your question via Facebook, Twitter @EMBLorg, Google+ or YouTube, tagged #EMBL40Q, or via the form

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Jul 312014
International Summer Science School Heidelberg 2014 at EMBL

We immensely enjoyed interacting with the participants of the International Summer Science School Heidelberg 2014. It has been an impressing group of international students who have joined us for the practical workshop at EMBL. We have done hands-on experiments in the training labs of the EMBL Advanced Training Center, explored the biology of the model system Zebrafish in the EMBL

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Mar 172015
New technique to chart protein networks in living cells

In a nutshell:

Fully automated single molecule measurements allow scientists to probe complex biological networks in living cells.
Technique holds promise for understanding of disease and drug discovery.
A new approach for studying the behaviour of proteins in living cells has been developed by an interdisciplinary team of biologists and physicists in the Cell Biology and Biophysics Unit, the Ellenberg group and the Advanced Light Microscopy Facility at the European Molecular Biology Laboratory in Heidelberg.

Described in a new study, published today in Nature Biotechnology, the approach allows scientists for the first time to follow the protein networks that drive a biological process in real time.

Which proteins interact with each other and where they meet within cells is of huge interest to scientists because it reveals the state and activity of the molecular machinery that drives the most fundamental functions of life such as the ability of cells to divide. The new technique will also be useful for scientists to investigate the mechanisms of disease and for pharmaceutical companies to explore new drug targets.

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